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Contrasting Effects of Histone Deacetylase Inhibitors on Reward and Aversive Olfactory Memories in the Honey Bee

Lockett, Gabrielle; Wilkes (previously Baglow), Fiona; Helliwell, Paul; Maleszka, Ryszard


Much of what we have learnt from rodent models about the essential role of epigenetic processes in brain plasticity has made use of aversive learning, yet the role of histone acetylation in aversive memory in the honey bee, a popular invertebrate model for both memory and epigenetics, was previously unknown. We examined the effects of histone deacetylase (HDAC) inhibition on both aversive and reward olfactory associative learning in a discrimination proboscis extension reflex (PER) assay. We...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Insects
DOI: 10.3390/insects5020377
Access Rights: Open Access


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