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Shape analysis of the corpus callosum in Alzheimer's disease and frontotemporal lobar degeneration subtypes

Walterfang, Mark; Luders, Eileen; Looi, Jeffrey; Rajagopalan, Priya; Velakoulis, Dennis; Thompson, Paul M; Lindberg, Olof; Ostberg, P; Nordin, Love E; Svensson, Leif; Wahlund, Lars-Olof


Morphology of the corpus callosum is a useful biomarker of neuronal loss, as different patterns of cortical atrophy help to distinguish between dementias such as Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD). We used a sophisticated morphometric analysis of the corpus callosum in FTLD subtypes including frontotemporal dementia (FTD), semantic dementia (SD), and progressive non-fluent aphasia (PNFA), and compared them to AD patients and 27 matched controls. FTLD patient...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Journal of Alzheimer's Disease
DOI: 10.3233/JAD-131853


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