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Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation

Bornancin, Frederic; Renner, Florian; Touil, Ratiba; Sic, Heiko; Kolb, Yeter; Touil-Allaoui, Ismahane; Rush, James S; Smith, Paul A; Bigaud, Marc; Junker-Walker, Ursula; Burkhart, Christoph; Dawson, Janet; Niwa, Satoru; Katopodis, Andreas; Nuesslein-Hildesheim, Barbara; Weckbecker, Gisbert; Zenke, Gerhard; Kinzel, Bernd; Traggiai, Elisabetta; Brenner, Dirk; Bruestle, Anne; St Paul, M; Zamurovic, Natasa; McCoy, Kathy D; Rolink, Antonius; Regnier, Catherine H; Mak, TW; Ohashi, Pamela; Patel, Dhavalkumar D; Calzascia, Thomas

Description

The paracaspase MALT1 plays an important role in immune receptor-driven signaling pathways leading to NF-κB activation. MALT1 promotes signaling by acting as a scaffold, recruiting downstream signaling proteins, as well as by proteolytic cleavage of mult

dc.contributor.authorBornancin, Frederic
dc.contributor.authorRenner, Florian
dc.contributor.authorTouil, Ratiba
dc.contributor.authorSic, Heiko
dc.contributor.authorKolb, Yeter
dc.contributor.authorTouil-Allaoui, Ismahane
dc.contributor.authorRush, James S
dc.contributor.authorSmith, Paul A
dc.contributor.authorBigaud, Marc
dc.contributor.authorJunker-Walker, Ursula
dc.contributor.authorBurkhart, Christoph
dc.contributor.authorDawson, Janet
dc.contributor.authorNiwa, Satoru
dc.contributor.authorKatopodis, Andreas
dc.contributor.authorNuesslein-Hildesheim, Barbara
dc.contributor.authorWeckbecker, Gisbert
dc.contributor.authorZenke, Gerhard
dc.contributor.authorKinzel, Bernd
dc.contributor.authorTraggiai, Elisabetta
dc.contributor.authorBrenner, Dirk
dc.contributor.authorBruestle, Anne
dc.contributor.authorSt Paul, M
dc.contributor.authorZamurovic, Natasa
dc.contributor.authorMcCoy, Kathy D
dc.contributor.authorRolink, Antonius
dc.contributor.authorRegnier, Catherine H
dc.contributor.authorMak, TW
dc.contributor.authorOhashi, Pamela
dc.contributor.authorPatel, Dhavalkumar D
dc.contributor.authorCalzascia, Thomas
dc.date.accessioned2015-12-13T22:16:25Z
dc.identifier.issn0022-1767
dc.identifier.urihttp://hdl.handle.net/1885/70854
dc.description.abstractThe paracaspase MALT1 plays an important role in immune receptor-driven signaling pathways leading to NF-κB activation. MALT1 promotes signaling by acting as a scaffold, recruiting downstream signaling proteins, as well as by proteolytic cleavage of mult
dc.publisherAmerican Association of Immunologists
dc.sourceJournal of Immunology
dc.titleDeficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume194
dc.date.issued2015
local.identifier.absfor110703 - Autoimmunity
local.identifier.ariespublicationa383154xPUB2444
local.type.statusPublished Version
local.contributor.affiliationBornancin, Frederic, NOvartis Institutes for BioMedical Research
local.contributor.affiliationRenner, Florian, Novartis Institutes for BioMedical Research
local.contributor.affiliationTouil, Ratiba, Novartis Institutes of BioMedical Research
local.contributor.affiliationSic, Heiko, Novartis Institutes of BioMedical Research
local.contributor.affiliationKolb, Yeter, Novartis Institutes of BioMedical Research
local.contributor.affiliationTouil-Allaoui, Ismahane, Novartis Institutes of BioMedical Research
local.contributor.affiliationRush, James S, Novartis Institutes of BioMedical Research
local.contributor.affiliationSmith, Paul A, Novartis Institutes of BioMedical Research
local.contributor.affiliationBigaud, Marc, Novartis Institutes of BioMedical Research
local.contributor.affiliationJunker-Walker, Ursula, Novartis Institutes of BioMedical Research
local.contributor.affiliationBurkhart, Christoph, Novartis Institutes of BioMedical Research
local.contributor.affiliationDawson, Janet, Novartis Insitutes of BioMedical Research
local.contributor.affiliationNiwa, Satoru, Novartis Institutes of BioMedical Research
local.contributor.affiliationKatopodis, Andreas, Novartis Institutes of BioMedical Research
local.contributor.affiliationNuesslein-Hildesheim, Barbara, Novartis Institutes of BioMedical Research
local.contributor.affiliationWeckbecker, Gisbert, Novartis Institutes of BioMedical Research
local.contributor.affiliationZenke, Gerhard, Novartis Institutes of BioMedical Research
local.contributor.affiliationKinzel, Bernd, Novartis Institutes of BioMedical Research
local.contributor.affiliationTraggiai, Elisabetta, Novartis Institutes of BioMedical Research
local.contributor.affiliationBrenner, Dirk, Ontario Cancer Institute
local.contributor.affiliationBruestle, Anne, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationSt Paul, M, Ontario Cancer Institute
local.contributor.affiliationZamurovic, Natasa, Novartis Institutes of BioMedical Research
local.contributor.affiliationMcCoy, Kathy D, University of Bern
local.contributor.affiliationRolink, Antonius, University of Basel
local.contributor.affiliationRegnier, Catherine H, Novartis Institutes of BioMedical Research
local.contributor.affiliationMak, TW, Ontario Cancer Institute
local.contributor.affiliationOhashi, PS, Ontario Cancer Institute
local.contributor.affiliationPatel, Dhavalkumar D, Novartis Institutes of BioMedical Research
local.contributor.affiliationCalzascia, Thomas, Novartis Institutes of BioMedical Research
local.description.embargo2037-12-31
local.bibliographicCitation.issue8
local.bibliographicCitation.startpage3723
local.bibliographicCitation.lastpage3734
local.identifier.doi10.4049/jimmunol.1402254
local.identifier.absseo920108 - Immune System and Allergy
dc.date.updated2015-12-11T07:26:04Z
local.identifier.scopusID2-s2.0-84927603501
CollectionsANU Research Publications

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