Voltage independence of vasomotion in isolated irideal arterioles of the rat
The cellular mechanisms underlying vasomotion of irideal arterioles from juvenile rats have been studied ng electrophysiological methods, ratiometric calcium measurements and video microscopy. Vasomotion was not affected by removal of the endothellium. Spontaneous contractions were preceded by spontaneous depolarizations. Both were abolished by the intracellular calcium chelator, BAPTA AM (20 μM), but not by ryanodine (10 μM), suggesting a dependence on the cyclical release of calcium from...[Show more]
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|Source:||Journal of Physiology|
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