Effectiveness of beads for tracking small-scale molecular motor dynamics
Investigations into molecular motor dynamics are increasingly focused on small-scale features of the motor's motion. We define performance measures of a common type of single-molecule motility assay, the bead assay, for its ability to detect such features. Using numerical models, we explore the dependence of assay performance on a number of experimentally controllable parameters, including bead size, optical force, and the method of attaching the bead to the motor. We find that the best...[Show more]
|Collections||ANU Research Publications|
|Source:||Physical Review E-Statistical, Nonlinear and Soft Matter Physics|
|01_Lade_Effectiveness_of_beads_for_2011.pdf||521.11 kB||Adobe PDF||Request a copy|
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