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Protein export into malaria parasite-infected erythrocytes: Mechanisms and functional consequences

Spillman, Natalie; Beck, Josh R; Goldberg, Daniel E


Phylum Apicomplexa comprises a large group of obligate intracellular parasites of high medical and veterinary importance. These organisms succeed intracellularly by effecting remarkable changes in a broad range of diverse host cells. The transformation of the host erythrocyte is particularly striking in the case of the malaria parasite Plasmodium falciparum. P. falciparum exports hundreds of proteins that mediate a complex cellular renovation marked by changes in the permeability, rigidity, and...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: Annual Review of Biochemistry
DOI: 10.1146/annurev-biochem-060614-034157


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