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Stiff chains inhibit and flexible chains promote protein adsorption to polyelectrolyte multilayers

Wu, Bo; Liu, Guangming; Zhang, Guangzhao; Craig, Vincent


We tested the hypothesis that the level of protein adsorption onto polyelectrolyte multilayers (PEMs) is influenced by the chain stiffness of the polymers forming the multilayer. The implication being that by altering the chain stiffness, PEMs can be formed that promote or inhibit protein adsorption. Protein adsorption to PEMs consisting of flexible and semi-flexible polyelectrolytes was investigated. The flexible polyelectrolytes were poly(sodium 4-styrene sulfonate) (PSS) and...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Soft Matter
DOI: 10.1039/c4sm00413b


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