The N-terminal TOG domain of Arabidopsis MOR1 modulates affinity for microtubule polymers
Microtubule-associated proteins of the highly conserved XMAP215/Dis1 family promote both microtubule growth and shrinkage, and move with the dynamic microtubule ends. The plant homologue, MOR1, is predicted to form a long linear molecule with five N-terminal TOG domains. Within the first (TOG1) domain, the mor1-1 leucine to phenylalanine (L174F) substitution causes temperature-dependent disorganization of microtubule arrays and reduces microtubule growth and shrinkage rates. By expressing the...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Cell Science|
|Access Rights:||Open Access|
|01_Lechner_The_N-terminal_TOG_domain_of_2012.pdf||2.54 MB||Adobe PDF|
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