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Functional role of peroxisome-proliferator-activated receptor γ in hepatocellular carcinoma

Wu, Chung W; Farrell, Geoffrey; Yu, Jun

Description

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Major risk factors of HCC include infection with hepatitis B or C viruses, alcohol and non-alcoholic fatty liver disease. HCC is difficult to diagnose at early stage, and has a very poor survival rate when diagnosed at a late stage. The majority of HCC-related deaths result from local invasion (to cause liver failure) or distant metastases. There is an urgent need to identify effective molecular targets for the treatment...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/70317
Source: Journal of Gastroenterology and Hepatology
DOI: 10.1111/j.1440-1746.2012.07213.x

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