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A total synthesis of herboxidiene methyl ester

Premraj, Rajaratnam; McLeod, Malcolm; Simpson, Gregory; Banwell, Martin


The total synthesis of the methyl ester, 35, of herboxidiene (1, a.k.a. GEX1A and TAN-1609), a polyketide displaying both herbicidal and anti-tumor activity, is described. The convergent reaction sequence involves, in its closing stages, the union of the

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Heterocycles
DOI: 10.3987/COM-12-12597


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