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Extensive histone post-translational modification in honey bees

Dickman, Mark J.; Kucharski, Robert; Maleszka, Ryszard; Hurd, Paul J.

Description

Histone post-translational modifications (PTMs) play a key role in regulating a variety of cellular processes including the establishment, maintenance and reversal of transcriptional programmes in eukaryotes. However, little is known about such modifications in the economically and ecologically important insect pollinator, the honey bee (Apis mellifera). Using mass spectrometry approaches, we show that histone H3.1, H3.3 and H4 of the honey bee are extensively modified by lysine acetylation and...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
URI: http://hdl.handle.net/1885/69920
Source: Insect Biochemistry and Molecular Biology
DOI: 10.1016/j.ibmb.2012.11.003

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