Skip navigation
Skip navigation

Associations between adipokines and obesity-related cancer

Da Paz Filho, Gilberto; Lim, Ee Lyn; Wong, Ma-Li; Licinio, Julio

Description

There is increasing evidence that obesity may have pathophysiological effects that extend beyond its well-known co-morbidities; in particular its role in cancer has received considerable epidemiological support. As adipose tissue becomes strongly established as an endocrine organ, two of its most abundant and most investigated adipokines, leptin and adiponectin, are also taken beyond their traditional roles in energy homeostasis, and are implicated as mediators of the effects of obesity on...[Show more]

dc.contributor.authorDa Paz Filho, Gilberto
dc.contributor.authorLim, Ee Lyn
dc.contributor.authorWong, Ma-Li
dc.contributor.authorLicinio, Julio
dc.date.accessioned2015-12-10T23:35:25Z
dc.identifier.issn1093-9946
dc.identifier.urihttp://hdl.handle.net/1885/69854
dc.description.abstractThere is increasing evidence that obesity may have pathophysiological effects that extend beyond its well-known co-morbidities; in particular its role in cancer has received considerable epidemiological support. As adipose tissue becomes strongly established as an endocrine organ, two of its most abundant and most investigated adipokines, leptin and adiponectin, are also taken beyond their traditional roles in energy homeostasis, and are implicated as mediators of the effects of obesity on cancer development. This review examines these dipokines in relation to the prostate, breast, colorectal, thyroid, renal, pancreatic, endometrial and oesophageal cancers, and how they may orchestrate the influence of obesity on the development of these malignancies.
dc.publisherFrontiers in Bioscience Inc.
dc.sourceFrontiers in Bioscience
dc.subjectKeywords: Adipocytokine; Adipokine; Adiponectin; Cancer; Leptin; Obesity; Review
dc.titleAssociations between adipokines and obesity-related cancer
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume16
dc.date.issued2011
local.identifier.absfor111202 - Cancer Diagnosis
local.identifier.ariespublicationf2965xPUB2141
local.type.statusPublished Version
local.contributor.affiliationDa Paz Filho, Gilberto, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLim, Ee Lyn, Trinity College
local.contributor.affiliationWong, Ma-Li, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLicinio, Julio, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.issue5
local.bibliographicCitation.startpage1634
local.bibliographicCitation.lastpage1650
local.identifier.doi10.2741/3810
local.identifier.absseo970111 - Expanding Knowledge in the Medical and Health Sciences
dc.date.updated2016-02-24T08:22:28Z
local.identifier.scopusID2-s2.0-79954988230
local.identifier.thomsonID000290094700003
CollectionsANU Research Publications

Download

File Description SizeFormat Image
01_Da Paz Filho_Associations_between_2011.pdf208.92 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  22 January 2019/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator