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Causes of death in infants admitted to Australian neonatal intensive care units between 1995 and 2006

Feng, Yvonne; Mohamed, Abdel-Latif; Bajuk, Barbara; Lui, Kei; Oei, Ju Lee

Description

Aim To compare causes and rates of mortality among infants admitted to 10 Australian neonatal intensive care units (NICUs) between 1995 and 2006. Methods: De-identified perinatal data from the Neonatal Intensive Care Units' (NICUS) Data Collection for 24131 infants were examined for causes and rates of death. The study period was divided into two epochs: I (1995-2000, n=11185 infants) and II (2001-2006, n=12946 infants). Results: A total of 2224 (9.2%) infants died in hospital. Mortality...[Show more]

dc.contributor.authorFeng, Yvonne
dc.contributor.authorMohamed, Abdel-Latif
dc.contributor.authorBajuk, Barbara
dc.contributor.authorLui, Kei
dc.contributor.authorOei, Ju Lee
dc.date.accessioned2015-12-10T23:35:08Z
dc.identifier.issn0803-5253
dc.identifier.urihttp://hdl.handle.net/1885/69724
dc.description.abstractAim To compare causes and rates of mortality among infants admitted to 10 Australian neonatal intensive care units (NICUs) between 1995 and 2006. Methods: De-identified perinatal data from the Neonatal Intensive Care Units' (NICUS) Data Collection for 24131 infants were examined for causes and rates of death. The study period was divided into two epochs: I (1995-2000, n=11185 infants) and II (2001-2006, n=12946 infants). Results: A total of 2224 (9.2%) infants died in hospital. Mortality decreased from 10.3% (1152/11185) in epoch I to 8.3% (1072/12946) in epoch II (p<0.001) due to improved survival in term infants. Extreme prematurity also decreased as a primary cause of death (118 (10.2%) vs 76 (7.1%), p=0.008). No infant >42-week gestation was admitted in epoch II. Congenital abnormalities were the most common cause of death (>20%) in both epochs, mostly in term rather than preterm infants (40.7% vs 13.9%, p<0.001). Age of death was unchanged between the two epochs (median 4, 1st, 3rd quartiles: 1,16days). Conclusion: Mortality rates have continued to decrease but improvement is predominantly due to improved survival of term infants and prevention of postdate deliveries. Congenital abnormalities continue to be the most common cause of death.
dc.publisherWiley-Blackwell
dc.sourceActa Paediatrica
dc.subjectKeywords: Aborigine; antepartum hemorrhage; article; Australia; birth weight; brain hemorrhage; cause of death; cesarean section; chronic lung disease; congenital disorder; corticosteroid therapy; female; gestational age; head circumference; hospital discharge; hum Causes and rates; Mortality; Neonatal intensive care; Trends
dc.titleCauses of death in infants admitted to Australian neonatal intensive care units between 1995 and 2006
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume102
dc.date.issued2013
local.identifier.absfor110303 - Clinical Microbiology
local.identifier.ariespublicationf5625xPUB2103
local.type.statusPublished Version
local.contributor.affiliationFeng, Yvonne, University of New South Wales
local.contributor.affiliationMohamed, Abdel-Latif, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationBajuk, Barbara, NSW Pregnancy and Newborn Services Network
local.contributor.affiliationLui, Kei, Royal Hospital for Women
local.contributor.affiliationOei, J, University of New South Wales
local.description.embargo2037-12-31
local.bibliographicCitation.issue1
local.bibliographicCitation.startpagee17
local.bibliographicCitation.lastpagee23
local.identifier.doi10.1111/apa.12039
dc.date.updated2016-02-24T08:54:10Z
local.identifier.scopusID2-s2.0-84870989176
CollectionsANU Research Publications

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