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Consequences of the recurrent MYD88 L265P somatic mutation for B cell tolerance

Wang, James; Jeelall, Yogeshraj; Beutler, Bruce; Horikawa, Keisuke; Goodnow, Christopher


MYD88L265P has recently been discovered as an extraordinarily frequent somatic mutation in benign monoclonal IgM gammopathy, Waldenström's macroglobulinemia, and diffuse large B cell lymphoma. In this study, we analyze the consequences for antigen-activa

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Journal of Experimental Medicine
DOI: 10.1084/jem.20131424
Access Rights: Open Access


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