Protection by methylproamine of irradiated human keratinocytes correlates with reduction of DNA damage
Purpose: The therapeutic ratio for ionising radiation treatment of tumour is a trade-off between normal tissue side-effects and tumour control. Application of a radioprotector to normal tissue can reduce side-effects. Here we study the effects of a new radioprotector on the cellular response to radiation. Methylproamine is a DNA-binding radioprotector which, on the basis of published pulse radiolysis studies, acts by repair of transient radiation-induced oxidative species on DNA. To...[Show more]
|Collections||ANU Research Publications|
|Source:||International Journal of Radiation Biology|
|01_MacKay_Protection_by_methylproamine_2011.pdf||302.54 kB||Adobe PDF||Request a copy|
|02_MacKay_Protection_by_methylproamine_2011.pdf||1.79 MB||Adobe PDF||Request a copy|
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