Tic22 is an essential chaperone required for protein import into the apicoplast
Most plastids proteins are post-translationally imported into organelles through multisubunit translocons. The TIC and TOC complexes perform this role in the two membranes of the plant chloroplast and in the inner two membranes of the apicoplasts of the apicomplexan parasites, Toxoplasma gondii and Plasmodium falciparum. Tic22 is a ubiquitous intermembrane translocon component that interacts with translocating proteins. Here, we demonstrate that T. gondii Tic22 is an apicoplast-localized...[Show more]
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|Source:||Journal of Biological Chemistry|
|01_Glaser_Tic22_is_an_essential_2012.pdf||1.51 MB||Adobe PDF||Request a copy|
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