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Nanoassemblies of Gd-DTPA-monooleyl and glycerol monooleate amphiphiles as potential MRI contrast agents

Gupta, Abhishek; Stait-Gardner, Timothy; De Campo, Liliana; Waddington, Lynne J; Kirby, N; Price, William Sydney; Moghaddam, Minoo

Description

Self-assembly of lipid-based amphiphiles into various supramolecular nanostructured particles has been used in creating novel nanomaterials with diverse applications in drug delivery and diagnostic imaging. Here we report on Gd(iii) chelated DTPA amphiphiles with an oleyl chain (Gd-DTPA-MO) incorporated within the self-assembly matrix of glycerol monooleate (GMO), an inverse cubic phase forming system, at varying compositions. The dispersed colloidal nanoassemblies were explored for their...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
URI: http://hdl.handle.net/1885/69171
Source: Journal of Materials Chemistry B
DOI: 10.1039/c3tb21069c

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