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The Plasmodium falciparum -infected red blood cell

Tilley, Leann; Dixon, Matthew W. A; Kirk, Kiaran


Plasmodium falciparum, the most virulent of the human malaria parasites, causes up to one million deaths per year. The parasite spends part of its lifecycle inside the red blood cells (RBCs) of its host. As it grows it ingests the RBC cytoplasm, digesting it in an acidic vacuole. Free haem released during haemoglobin digestion is detoxified by conversion to inert crystals of haemozoin. Malaria pathology is evident during the blood stage of the infection and is exacerbated by adhesion of...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: The International Journal of Biochemistry and Cell Biology
DOI: 10.1016/j.biocel.2011.03.012


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