Holleley, Clare E.; Nichols, Richard A.; Whitehead, Michael; Adamack, Aaron T.; Gunn, Melissa R.; Sherwin, William
The effective population size (N e) is a key parameter in evolutionary and population genetics. Single-sample N e estimation provides an alternative to traditional approaches requiring two or more samples. Single-sample methods assume that the study population has no genetic sub-structure, which is unlikely to be true in wild populations. Here we empirically investigated two single-sample estimators (onesamp and L d N e) in replicated and controlled genetically structured populations of...[Show more]
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