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Brain volumes in late life: gender, hormone treatment, and estrogen receptor variants

Ryan, Joanne; Artero, Sylvaine; Carrière, Isabelle; Scali, Jacqueline; Maller, Jerome J.; Meslin, Chantal; Ritchie, Karen; Scarabin, Pierre-Yves; Ancelin, Marie-Laure


Structural imaging studies suggest gender differences in brain volumes; however, whether hormone treatment (HT) can protect against age-related structural changes remains unknown, and no prior neuroimaging study has investigated potential interactions between HT and estrogen receptor (ESR) polymorphisms. Magnetic resonance imaging was used to measure gray and white matter, hippocampal volume, corpus callosum, cerebrospinal fluid (CSF), total intracranial volume (ICV) and white matter lesions...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Journal article
Source: Neurobiology of Aging
DOI: 10.1016/j.neurobiolaging.2013.09.026


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