Identification of a novel antigen cross-presenting cell type in spleen
Tan, Jonathan; Quah, Ben; Griffiths, Kristin; Periasamy, Pravin; Hey, Ying Ying; O'Neill, Helen
Description
Antigen-presenting cells (APC), like dendritic cells (DC), are essential for T-cell activation, leading to immunity or tolerance. Multiple DC subsets each play a unique role in the immune response. Here, a novel splenic dendritic-like APC has been characterized in mice that has immune function and cell surface phenotype distinct from other, described DC subsets. These were identified as a cell type continuously produced in spleen long-term cultures (LTC) and have anin vivoequivalent cell type...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2011 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/68690 |
Source: | Journal of Cellular and Molecular Medicine |
DOI: | 10.1111/j.1582-4934.2010.01089.x |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Tan_Identification_of_a_novel_2011.pdf | 870.76 kB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 20 July 2017/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator