Identification of a novel antigen cross-presenting cell type in spleen
Antigen-presenting cells (APC), like dendritic cells (DC), are essential for T-cell activation, leading to immunity or tolerance. Multiple DC subsets each play a unique role in the immune response. Here, a novel splenic dendritic-like APC has been characterized in mice that has immune function and cell surface phenotype distinct from other, described DC subsets. These were identified as a cell type continuously produced in spleen long-term cultures (LTC) and have anin vivoequivalent cell type...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Cellular and Molecular Medicine|
|01_Tan_Identification_of_a_novel_2011.pdf||870.76 kB||Adobe PDF|
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