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Characterisation of a highly sensitive troponin I assay and its application to a cardio-healthy population

Koerbin, Gus; Tate, Jill; Potter, Julia; Cavanaugh, Juleen; Glasgow, Nicholas; Hickman, Peter


Background: Abbott Diagnostics have developed a new highly sensitive troponin I (hs-TnI) assay. We have assessed its analytical characteristics and applied the assay to a population of apparently cardio-healthy persons. Methods: We assessed imprecision, bias compared to the previous generation assay, matrix effects, and interferences and applied the assay to an apparently healthy population, deriving the 99th percentile limit of the distribution of values in reference populations for men and...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Clinical Chemistry and Laboratory Medicine
DOI: 10.1515/cclm-2011-0540


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