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Depression in elderly persons subject to childhood maltreatment is not modulated by corpus callosum and hippocampal loss

Ritchie, K; Jaussent, Isabelle; Portet, Forence; Courtet, Philippe; Malafosse, Alain; Maller, Jerome J.; Meslin, Chantal; Bonafe, Alain; Le Bars, Emmanuelle; Menjot de Champfleur, Nicolas; Artero, Sylvaine; Ancelin, Marie-Laure


Childhood adversity has been observed to engender structural changes in the hippocampus and corpus callosum associated with increased risk for depression in childhood and early adulthood. This study investigated this association in the elderly. Corpus callosum area and hippocampal volume were measured from structural MRI in 427 community dwelling elderly. Information on childhood adversity was obtained in the course of a clinical examination using a questionnaire covering multiple aspects of...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Journal of Affective Disorders
DOI: 10.1016/j.jad.2012.03.035


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