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Promoting engraftment of transplanted neural stem cells/progenitors using biofunctionalised electrospun scaffolds

Wang, Ting-Yi; Forsythe, John S.; Nisbet, David; Parish, Clare L.

Description

With the brain's limited capacity for repair, new and innovative approaches are required to promote regeneration. While neural transplantation for a number of neural disease/injuries have been demonstrated, major limitations in the field include poor cell survival and integration. This, in part, is due to the non-conducive environment of the adult brain, failing to provide adequate chemical and physical support for new neurons. Here we examine the capacity of fibrous poly ε-caprolactone (PCL)...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/68327
Source: Biomaterials
DOI: 10.1016/j.biomaterials.2012.09.013

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