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Isomer-specific comparisons of the hydrolysis of synthetic pyrethroids and their fluorogenic analogues by esterases from the cotton bollworm Helicoverpa armigera

Yuan, G; Li, Y; Farnsworth, Claire; Coppin, C. W; Devonshire, A. L; Scott, C; Russell, R. J; Wu, Y; Oakeshott, John Graham


The low aqueous solubility and chiral complexity of synthetic pyrethroids, together with large differences between isomers in their insecticidal potency, have hindered the development of meaningful assays of their metabolism and metabolic resistance to them. To overcome these problems, Shan and Hammock (2001) [7] therefore developed fluorogenic and more water-soluble analogues of all the individual isomers of the commonly used Type 2 pyrethroids, cypermethrin and fenvalerate. The analogues have...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: Pesticide Biochemistry and Physiology
DOI: 10.1016/j.pestbp.2014.12.010


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