Yuan, G; Li, Y; Farnsworth, Claire; Coppin, C. W; Devonshire, A. L; Scott, C; Russell, R. J; Wu, Y; Oakeshott, John Graham
The low aqueous solubility and chiral complexity of synthetic pyrethroids, together with large differences between isomers in their insecticidal potency, have hindered the development of meaningful assays of their metabolism and metabolic resistance to them. To overcome these problems, Shan and Hammock (2001)  therefore developed fluorogenic and more water-soluble analogues of all the individual isomers of the commonly used Type 2 pyrethroids, cypermethrin and fenvalerate. The analogues have...[Show more]
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