Map Making in the 21st Century: Charting Breast Cancer Susceptibility Pathways in Rodent Models
Genetic factors play an important role in determining risk and resistance to increased breast cancer. Recent technological advances have made it possible to analyze hundreds of thousands of single nucleotide polymorphisms in large-scale association studies in humans and have resulted in identification of alleles in over 20 genes that influence breast cancer risk. Despite these advances, the challenge remains in identifying what the functional polymorphisms are that confer the increased risk,...[Show more]
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|Source:||Journal of Mammary Gland Biology and Neoplasia|
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