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Probing the closed-loop model of mRNA translation in living cells

Archer, Stuart; Shirokikh, Nikolay; Hallwirth, Claus; Beilharz, Traude; Preiss, Thomas

Description

The mRNA closed-loop, formed through interactions between the cap structure, poly(A) tail, eIF4E, eIF4G and PAB, features centrally in models of eukaryotic translation initiation, although direct support for its existence in vivo is not well established.

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
URI: http://hdl.handle.net/1885/67519
Source: RNA Biology
DOI: 10.1080/15476286.2015.1017242

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