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Longevity Is Linked to Mitochondrial Mutation Rates in Rockfish: A Test Using Poisson Regression

Hua, Xia; Cowman, Peter; Warren, Dan; Bromham, Lindell

Description

The mitochondrial theory of ageing proposes that the cumulative effect of biochemical damage in mitochondria causes mitochondrial mutations and plays a key role in ageing. Numerous studies have applied comparative approaches to test one of the predictions of the theory: That the rate of mitochondrial mutations is negatively correlated with longevity. Comparative studies face three challenges in detecting correlates of mutation rate: Covariation of mutation rates between species due to ancestry,...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
URI: http://hdl.handle.net/1885/67518
Source: Molecular Biology and Evolution
DOI: 10.1093/molbev/msv137

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