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Transfer of glutamine between astrocytes and neurons

Broer, Stefan; Brookes, Neville


The export of glutamine from astrocytes, and the uptake of glutamine by neurons, are integral steps in the glutamate-glutamine cycle, a major pathway for the replenishment of neuronal glutamate. We review here the functional and molecular identification of the transporters that mediate this transfer. The emerging picture of glutamine transfer in adult brain is of a dominant pathway mediated by system N transport (SN1) in astrocytes and system A transport (SAT/ATA) in neurons. The participating...[Show more]

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
Source: Journal of Neurochemistry
DOI: 10.1046/j.1471-4159.2001.00322.x


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