Size and sulfation are critical for the effect of heparin on APP processing and Aβ production
Alzheimer's disease is associated with abnormal accumulation of Aβ, which is produced from the β-amyloid precursor protein (APP) by the β-site APP-cleaving enzyme (BACE1) and Î-secretase. Our previous studies showed that heparin can decrease APP proce
|Collections||ANU Research Publications|
|Source:||Journal of Neurochemistry|
|01_Cui_Size_and_sulfation_are_2012.pdf||653.09 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.