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The renin-angiotensin system and cancer: Old dog, new tricks

George, Amee; Thomas, Walter G.; Hannan, Ross


For cancers to develop, sustain and spread, the appropriation of key homeostatic physiological systems that influence cell growth, migration and death, as well as inflammation and the expansion of vascular networks are required. There is accumulating molecular and in vivo evidence to indicate that the expression and actions of the reninĝ€"angiotensin system (RAS) influence malignancy and also predict that RAS inhibitors, which are currently used to treat hypertension and cardiovascular disease,...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Nature Reviews Cancer
DOI: 10.1038/nrc2945


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