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Vitamin C supplementation in kidney failure: Effect on uraemic symptoms

Singer, Richard

Description

Background. Vitamin C (ascorbate) deficiency and symptoms consistent with deficiency (fatigue, myalgia, dyspnoea, gingivitis, cardiovascular instability and depression) are common in patients with renal failure. This study aimed to determine if supplementation with ascorbate in patients with severe renal failure improved symptoms or cardiovascular stability, or was associated with adverse effects.Methods. The study was a 3-month, double-blind, randomized trial of ascorbic acid 250 mg or...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/67130
Source: Nephrology Dialysis Transplantation
DOI: 10.1093/ndt/gfq412

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