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Dynamic evolution of venom proteins in squamate reptiles

Casewell, Nicholas; Huttley, Gavin Austin; Wuster, Wolfgang

Description

Phylogenetic analyses of toxin gene families have revolutionised our understanding of the origin and evolution of reptile venoms, leading to the current hypothesis that venom evolved once in squamate reptiles. However, because of a lack of homologous squamate non-toxin sequences, these conclusions rely on the implicit assumption that recruitments of protein families into venom are both rare and irreversible. Here we use sequences of homologous non-toxin proteins from two snake species to test...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/67119
Source: Nature Communications
DOI: 10.1038/ncomms2065

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