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Has anti-D prophylaxis increased the rate of positive direct antiglobulin test results and can the direct antiglobulin test predict need for phototherapy in Rh/ABO incompatibility?

Dillon, Alexander; Chaudhari, Tejasvi; Crispin, Philip; Shadbolt, Bruce; Kent, Alison


Aim: To determine the impact of Rhesus (Rh) D prophylaxis on positive direct antiglobulin test (DAT) results and ability of a DAT grade to predict an infant's need for phototherapy. Methods: Laboratory and infant medical records were reviewed for DAT status, DAT grade, interventions for hyperbilirubinemia including phototherapy, blood transfusion, exchange transfusion and intravenous immunoglobulin. Two epochs of DAT results were reviewed, the first in the era prior to Rh D prophylaxis, the...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Journal of Paediatrics and Child Health
DOI: 10.1111/j.1440-1754.2010.01888.x


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