The haemagglutinin gene, but not the neuraminidase gene, of Spanish flu was a recombinant
Published analyses of the sequences of three genes from the 1918 Spanish influenza virus have cast doubt on the theory that it came from birds immediately before the pandemic. They showed that the virus was of the H1N1 subtype lineage but more closely related to mammal-infecting strains than any known bird-infecting strain. They provided no evidence that the virus originated by gene reassortment nor that the virus was the direct ancestor of the two lineages of H1N1 viruses currently found in...[Show more]
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|Source:||Proceedings of the Royal Society of London Series B: Biological Sciences|
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