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Postprandial hyperinsulinemia is universal in non-diabetic patients with nonalcoholic fatty liver disease

Manchanayake, Jayani; Chitturi, Shivakumar; Nolan, Christopher; Farrell, Geoffrey

Description

Background and Aims: Despite strong associations between non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D), it is unclear which patients need oral glucose tolerance testing (OGTT). Relationships between hyperglycemia, postprandial hyperinsulinemia and NAFLD severity also need clarification. Methods: Among 111 consecutive NAFLD patients, 35 had established T2D; 70 of the remaining 76 underwent 75G OGTT with fasting, 60 and 120min insulin. Hepatic fibrotic severity was estimated...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/66732
Source: Journal of Gastroenterology and Hepatology
DOI: 10.1111/j.1440-1746.2010.06528.x

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