Manchanayake, Jayani; Chitturi, Shivakumar; Nolan, Christopher; Farrell, Geoffrey
Background and Aims: Despite strong associations between non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D), it is unclear which patients need oral glucose tolerance testing (OGTT). Relationships between hyperglycemia, postprandial hyperinsulinemia and NAFLD severity also need clarification. Methods: Among 111 consecutive NAFLD patients, 35 had established T2D; 70 of the remaining 76 underwent 75G OGTT with fasting, 60 and 120min insulin. Hepatic fibrotic severity was estimated...[Show more]
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