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Severe pertussis in infants: Estimated impact of first vaccine dose at 6 versus 8 weeks in Australia

Foxwell, A. Ruth; McIntyre, Peter; Quinn, Helen; Roper, Katrina; Clements, Mark

Description

We estimated the potential benefits of advancing the first dose of pertussis vaccine for infants from 8 to 6 weeks of age, using Australian national disease databases. Infants had notification rates 3-fold greater than the general population and accounted for 52% of recorded hospitalizations. Infants 1 and 2 months of age had notification rates 3.5 times (95% CI: 2.7-4.5) higher than infants 3 to 11 months of age. Estimation of acceleration of the vaccine to 6 weeks of age reduced average...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/66514
Source: The Pediatric Infectious Disease Journal
DOI: 10.1097/INF.0b013e3181f43906

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