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Increased urinary podocytes following indomethacin suggests drug-induced glomerular injury

Kent, Alison; Brown, Linda; Broom, Margaret; Broomfield, Amy; Dahlstrom, Jane

Description

Background Preterm infants are delivered while glomerulo-genesis is ongoing and may be exposed to insults, including medications that may affect renal development. Podocytes detected in the urine are an indicator of glomerular injury. The aims of this study were to determine whether preterm and term infants excrete podocytes in their urine and whether exposure to gentamicin and indomethacin increase podo-cyte excretion in their urine. Methods Preterm infants <33 weeks gestation had urine...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/66424
Source: Pediatric Nephrology
DOI: 10.1007/s00467-012-2111-2

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