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Function and structure of heterodimeric amino acid transporters

Wagner, Carsten; Lang, Florian; Broer, Stefan

Description

Heterodimeric amino acid transporters are comprised of two subunits, a polytopic membrane protein (light chain) and an associated type II membrane protein (heavy chain). The heavy chain rbAT (related to bo,+ amino acid transporter) associates with the light chain bo,+ AT (bo,+ amino acid transporter) to form the amino acid transport system bo,+, whereas the homologous heavy chain 4F2hc interacts with several light chains to form system L (with LAT1 and LAT2), system y+L (with y+LAT1 and...[Show more]

CollectionsANU Research Publications
Date published: 2001
Type: Journal article
URI: http://hdl.handle.net/1885/66362
Source: American Journal of Physiology - Cell Physiology

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