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Protein elemental sparing and codon usage bias are correlated among bacteria

Bragg, Jason; Quigg, Antonietta; Raven, John A.; Wagner, Andreas


Highly expressed proteins can exhibit relatively small material costs, in terms of the quantities of carbon (C), nitrogen (N) or sulphur (S) atoms they contain. This 'elemental sparing' probably reflects selection to reduce the quantities of potentially growth-limiting elements in abundant proteins, but the evolutionary mechanisms for adaptive elemental sparing are still poorly understood. Here, we predict that the extent of 'elemental sparing' in highly expressed proteins will vary among...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Molecular Ecology
DOI: 10.1111/j.1365-294X.2012.05529.x


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