Cardiac troponin may be released by ischemia alone, without necrosis
Hickman, Peter; Potter, Julia; Aroney, Con; Koerbin, Gus; Southcott, Emma K; Wu, Allan; Roberts, M
Description
Whilst it is formally stated that cardiac troponin is only released when cardiac myocytes undergo necrosis, there are a number of clinical situations where troponin is present in the circulation, without any apparent cardiac injury. In these cases, troponin half-life in the circulation is usually substantially shorter than that seen when troponin is released following myocardial infarction with frank necrosis. A mechanism has been described in liver, where large cytoplasmic molecules can pass...[Show more]
Collections | ANU Research Publications |
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Date published: | 2010 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/66029 |
Source: | Clinica Chimica Acta |
DOI: | 10.1016/j.cca.2009.12.009 |
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01_Hickman_Cardiac_troponin_may_be_2010.pdf | 598.19 kB | Adobe PDF | Request a copy |
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