Becker, Stephan T; Bolte, H; Schunemann, K; Seitz, H; Bara, J J; Beck-Broichsitter, B E; Russo, Paul; Wiltfang, J; Warnke, Patrick H
When bone morphogenetic protein (BMP) is delivered to matrices in vivo may affect tissue engineered bone constructs for jaw reconstruction after cancer surgery. This study compared the effects of BMP application at different times after matrix implantation for heterotopic bone induction in a rat model. Hydroxyapatite blocks were implanted unilaterally onto the surface of the latissimus dorsi muscle. A second block was implanted onto the contralateral muscle after 1, 2 or 4 weeks and 200 μg...[Show more]
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