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Biomechanics of chiasmal compression: Sensitivity of the mechanical behaviours of nerve fibres to variations in material property and geometry

Wang, Xiaofei; Neely, Andrew; McIlwaine, Gawn G.; Lueck, Christian


The mechanism of bitemporal hemianopia is still unclear. Previous research suggested that the nerve fibre packing pattern may contribute to the selective damage of nasal (crossed) nerve fibres. Numerical models were built using finite element modelling to study the biomechanics of optic nerve fibres. The sensitivity of the mechanical behaviours of the nerve fibres to variations of five parameters in the nerve fibre model were investigated using design of experiments (DOE). Results show that the...[Show more]

CollectionsANU Research Publications
Date published: 2014
Type: Conference paper
Source: 11th World Congress on Computational Mechanics, WCCM 2014, 5th European Conference on Computational Mechanics, ECCM 2014 and 6th European Conference on Computational Fluid Dynamics, ECFD 2014


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