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Sequence polymorphisms of MC1R gene and their association with depression and antidepressant response

Wu, Gui-Sheng; Luo, Huai-Rong; Dong, Chuanhui; Mastronardi, Claudio; Licinio, Julio; Wong, Ma-Li


Objective: Melanocortin 1 receptor (MC1R) is involved in various functions, such as pigmentation, antipyretic and anti-inflammatory actions, development of melanoma, susceptibility to ultraviolet-induced sun damage, modification of oculocutaneous albinism, development of freckles, and mediation of female-specific mechanisms of analgesia. MC1R's natural agonists include α-melanocyte-stimulating hormone and corticotrophin (ACTH1-39), which are important components of hypothalamic pituitary...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Psychiatric Genetics
DOI: 10.1097/YPG.0b013e32834133d2


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