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Initiating head development in mouse embryos: Integrating signalling and transcriptional activity

Arkell, Ruth; Tam, Patrick


The generation of an embryonic body plan is the outcome of inductive interactions between the progenitor tissues that underpin their specification, regionalization and morphogenesis. The intercellular signalling activity driving these processes is deployed in a time- and site-specific manner, and the signal strength must be precisely controlled. Receptor and ligand functions are modulated by secreted antagonists to impose a dynamic pattern of globally controlled and locally graded signals onto...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Open Biology
DOI: 10.1098/rsob.120030
Access Rights: Open Access


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