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Treating primary hypothyroidism with weekly doses of levothyroxine: A randomized, single-blind, crossover study [tratamento de hipotiroidismo primário com doses semanais de levotiroxina: Um estudo randomizado, unicego, crossover

BORNSCHEIN, Andressa; Da Paz Filho, Gilberto; Graf, Hans; Amaral de Carvalho, Gisah


Objective: Compliance to levothyroxine treatment in hypothyroidism is compromised by daily schedule, and a weekly dose may be an alternative. Subjects and methods: This was a randomized, crossover study. Fourteen females were assigned to daily or weekly doses of LT4. After six weeks, they switched regimens. Thyroid parameters were measured at baseline, and after 42 and 84 days. Echocardiogram and hyperthyroidism symptoms were evaluated before and four hours after LT4 intake. Results: In the...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Arquivos Brasileiros de Endocrinologia e Metabologia
DOI: 10.1590/S0004-27302012000400006


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