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Methionine transport in the malaria parasite Plasmodium falciparum

Cobbold, Simon; Martin, Rowena; Kirk, Kiaran

Description

The intraerythrocytic malaria parasite, Plasmodium falciparum, derives amino acids from the digestion of host cell haemoglobin. However, it also takes up amino acids from the extracellular medium. Isoleucine is absent from adult human haemoglobin and an exogenous source of isoleucine is essential for parasite growth. An extracellular source of methionine is also important for the normal growth of at least some parasite strains. In this study we have characterised the uptake of methionine by P....[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/65296
Source: International Journal for Parasitology
DOI: 10.1016/j.ijpara.2010.09.001

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