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Inflammation location, but not type, determines the increase in TGF-β1 and IGF-1 expression and collagen deposition in IBD intestine

Lawrance, I; Maxwell, Lesley; Doe, W

Description

Background and Aims: Inflammatory bowel disease (IBD) is frequently complicated by extracellular matrix (ECM) changes that may result in fibrosis. Transforming growth factor (TGF)-β1 and insulin-like growth factor (IGF)-1 mediate numerous ECM changes. Ou

dc.contributor.authorLawrance, I
dc.contributor.authorMaxwell, Lesley
dc.contributor.authorDoe, W
dc.date.accessioned2015-12-10T23:16:23Z
dc.date.available2015-12-10T23:16:23Z
dc.identifier.issn1078-0998
dc.identifier.urihttp://hdl.handle.net/1885/65039
dc.description.abstractBackground and Aims: Inflammatory bowel disease (IBD) is frequently complicated by extracellular matrix (ECM) changes that may result in fibrosis. Transforming growth factor (TGF)-β1 and insulin-like growth factor (IGF)-1 mediate numerous ECM changes. Ou
dc.publisherLippincott Williams & Wilkins
dc.sourceInflammatory Bowel Diseases
dc.subjectKeywords: collagen; collagen type 1; collagen type 2; messenger RNA; somatomedin C; transforming growth factor beta1; article; colon Crohn disease; controlled study; disease classification; electron microscopy; enteritis; extracellular matrix; fibrosis; human; huma Collagen; IGF-1; Inflammatory bowel disease; Inflammatory infiltrate; TGF-ß1
dc.titleInflammation location, but not type, determines the increase in TGF-β1 and IGF-1 expression and collagen deposition in IBD intestine
dc.typeJournal article
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.citationvolume7
dc.date.issued2001
local.identifier.absfor060405 - Gene Expression (incl. Microarray and other genome-wide approaches)
local.identifier.ariespublicationMigratedxPub1041
local.type.statusPublished Version
local.contributor.affiliationLawrance, I, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMaxwell, Lesley, Canberra Hospital
local.contributor.affiliationDoe, W, College of Medicine, Biology and Environment, ANU
local.bibliographicCitation.issue1
local.bibliographicCitation.startpage16
local.bibliographicCitation.lastpage26
dc.date.updated2015-12-10T09:52:34Z
local.identifier.scopusID2-s2.0-0034997565
CollectionsANU Research Publications

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