Endogenous endophthalmitis: 10-year experience at a tertiary referral centre
-
Altmetric Citations
Connell, Paul; O'Neill, E C; Fabinyi, D; Islam, FMA; Buttery, R; McCombe, M; Essex, Rohan; Roufail, E; Clark, B; Chiu, D; Campbell, W; Allen, P
Description
Purpose Endogenous endophthalmitis (EE) is a sight-threatening emergency and the aetiology is often multifactorial. Delayed diagnosis may exacerbate the poor visual prognosis. We describe the management and visual outcomes of EE presenting to a tertiary referral centre.Patients and Methods A prospective consecutive case series of 64 patients presenting with presumed EE from 1997 to 2007 to the Royal Victorian Eye and Ear Hospital were included. All data were collected in a standardized manner....[Show more]
dc.contributor.author | Connell, Paul | |
---|---|---|
dc.contributor.author | O'Neill, E C | |
dc.contributor.author | Fabinyi, D | |
dc.contributor.author | Islam, FMA | |
dc.contributor.author | Buttery, R | |
dc.contributor.author | McCombe, M | |
dc.contributor.author | Essex, Rohan | |
dc.contributor.author | Roufail, E | |
dc.contributor.author | Clark, B | |
dc.contributor.author | Chiu, D | |
dc.contributor.author | Campbell, W | |
dc.contributor.author | Allen, P | |
dc.date.accessioned | 2015-12-10T23:16:21Z | |
dc.identifier.issn | 0950-222X | |
dc.identifier.uri | http://hdl.handle.net/1885/65022 | |
dc.description.abstract | Purpose Endogenous endophthalmitis (EE) is a sight-threatening emergency and the aetiology is often multifactorial. Delayed diagnosis may exacerbate the poor visual prognosis. We describe the management and visual outcomes of EE presenting to a tertiary referral centre.Patients and Methods A prospective consecutive case series of 64 patients presenting with presumed EE from 1997 to 2007 to the Royal Victorian Eye and Ear Hospital were included. All data were collected in a standardized manner. Outcome measures included: visual acuity, microbial profiles, and vitrectomy rate. Results In total, 64 cases of EE were identified over the study period with a mean age of 57.5 years, and 53.5% were male. Presenting acuities ranged from Snellen 6/6 to no perception of light (NPL). Identifiable risk factors were present in 78.1%, with the majority related to intravenous drug abuse. A 64.1% culture positivity rate was recorded. A vitrectomy rate of 57, 56, and 21% was recorded in documented bacterial, fungal, and no growth cases, respectively. Final Snellen acuities ranged from 6/6 to NPL. A total of 5 out of 64 eyes were enucleated, of which 3 identified Klebsiellaspecies. Better visual outcome was documented in fungal cases. Conclusion EE is a serious ocular condition and has a varied aetiology. Visual outcomes are often poor, irrespective of the method of management. Fungal aetiology often confers a better prognosis, and vitrectomy is advocated for bacterial proven cases. & 2011 Macmillan Publishers Limited. All rights reserved. | |
dc.publisher | Nature Publishing Group | |
dc.source | Eye | |
dc.subject | Keywords: adult; aged; article; bacterium culture; endogenous endophthalmitis; enucleation; female; fungal endophthalmitis; fungus culture; human; intravenous drug abuse; Klebsiella; major clinical study; male; microbial activity; outcome assessment; prognosis; pro drug abuse; endogenous endophthalmitis; microbiology; risk factors; visual acuity | |
dc.title | Endogenous endophthalmitis: 10-year experience at a tertiary referral centre | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.identifier.citationvolume | 25 | |
dc.date.issued | 2011 | |
local.identifier.absfor | 111399 - Optometry and Ophthalmology not elsewhere classified | |
local.identifier.ariespublication | f2965xPUB1038 | |
local.type.status | Published Version | |
local.contributor.affiliation | Connell, Paul, University of Melbourne | |
local.contributor.affiliation | O'Neill, E C, University of Melbourne | |
local.contributor.affiliation | Fabinyi, D, The Royal Victorian Eye and Ear Hospital | |
local.contributor.affiliation | Islam, FMA, University of Melbourne | |
local.contributor.affiliation | Buttery, R, The Royal Victorian Eye and Ear Hospital | |
local.contributor.affiliation | McCombe, M, The Royal Victorian Eye and Ear Hospital | |
local.contributor.affiliation | Essex, Rohan, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Roufail, E, The Royal Victorian Eye and Ear Hospital | |
local.contributor.affiliation | Clark, B, The Royal Victorian Eye and Ear Hospital | |
local.contributor.affiliation | Chiu, D, The Royal Victorian Eye and Ear Hospital | |
local.contributor.affiliation | Campbell, W, University of Melbourne | |
local.contributor.affiliation | Allen, P, The Royal Victorian Eye and Ear Hospital | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.issue | 1 | |
local.bibliographicCitation.startpage | 66 | |
local.bibliographicCitation.lastpage | 72 | |
local.identifier.doi | 10.1038/eye.2010.145 | |
dc.date.updated | 2016-02-24T08:08:21Z | |
local.identifier.scopusID | 2-s2.0-78651352558 | |
Collections | ANU Research Publications |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Connell_Endogenous_endophthalmitis:_2011.pdf | 256.48 kB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator