Segregation of B Lymphocytes into Stationary Apoptotic and Migratory Proliferating Subpopulations in Agglomerate Cultures with Ileal Epithelium
The B lymphocyte-epithelial cell interactions that define the microenvironment of the ileal Peyer's patch, the primary B lymphocyte organ of the fetal lamb, have been replicated in tissue culture. Mixed suspensions of ileal epithelial cells, lymphocytes and fibroblasts from fetuses of 63-103 days of gestation organized into macroscopically visible agglomerates within 72 h. These agglomerates contained translucent spherical cavities and were enclosed within a marginal cell layer and surrounded...[Show more]
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|Source:||European Journal of Immunology|
|01_Alitheen_Segregation_of_B_Lymphocytes_2001.pdf||483.45 kB||Adobe PDF||Request a copy|
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